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due to its implications in the metabolism of carbohydrates and lipids

DNMT1 activity assay A radiometric assay was performed by RBC using 100 M 5 nM SAH as an inhibitor positive control

We have also found that desnutrin/ATGL is downregulated in ob/ob and db/db mice, further supporting a role for the enzyme in fat breakdown and suggesting a possible contributory role in the development of obesity (130)