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In light of its superior safety profile, Health Canada mandated a label change in 2013 advising thorough consideration of NRT before prescribing either varenicline or bupropion to any smoker, further stating that in many cases, nicotine replacement therapy should be tried before prescribing varenicline or bupropion [9], emphasizing the need to optimize the effectiveness of this first-line medication

But an escalator was re-introduced in 2010 at one per cent above inflation, which was then hiked to two per cent above inflation in 2011

Studies indicate that Bupropion can nearly double the chances of quitting smoking compared to placebo

Representatives of tobacco organization Altria Group Inc