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However, both anti-CD147 metuximab and anti-CD147 scFv cannot differentiate membranous CD147 from mitochondrial CD147

They also showed in this paper that feeding the low-protein diet during the dosing period led to serious cases of liver toxicity: Some degree of bile duct proliferation was observed in all animals dosed with AFB1

Jointly, these reports suggest that preventing maladaptive metabolic reprogramming of inflammatory cells in the CNS and preserving mitochondrial respiration may help to combat neuroinflammation in PD