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26 The association between increased levels of NNK uptake and higher risk for lung cancer is completely plausible based on the powerful genotoxic carcinogenicity of NNK for the lung that has been observed in studies with mice, rats, hamsters, and ferrets treated with NNK, including some studies which used very low doses

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With 40 million hand-rolled and 300 million machine-made cigars per year, it ranks among the largest cigar manufacturers worldwide