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[13] Further research over the last decade has shed new light on the importance of L-carnitine as a regulator of skeletal muscle fuel selection, which means it is needed to determine whether muscle tissue utilizes carbohydrates or fat for energy

A 1994 in vivo study by Natera, Jiang, and Ng extended the observation into a whole animal, reporting that chronic administration of synthetic hGH 177 to 191 to genetically obese (ob/ob) mice was associated with reduced cumulative body-weight gain and reduced adipose mass relative to controls [2]

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They can assess whether the symptoms are genuinely related to the supplement, investigate alternative causes, and determine the most appropriate management strategy