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These compounds include the bile salts , cholesterol and related compounds, and certain hormones (such as cortisone and the sex hormones)

Rosenson RS, Brewer HB, Jr., Davidson WS, Fayad ZA, Fuster V, Goldstein J, Hellerstein M, Jiang XC, Phillips MC, Rader DJ, Remaley AT, Rothblat GH, Tall AR, Yvan-Charvet L

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The reverse cholesterol transport (RCT) pathway involving high-density lipoprotein (HDL) is an important process to maintain the balance of cholesterol metabolism, and promotes the efflux of free cholesterol from macrophages ( -/- mice and found that CD36 and SRA1 levels were increased in macrophages in TMAO-treated mice compared with control mice ( via a bile salt export pump (BSEP) and finally excreted with feces ( -/- mice ( Inflammatory response Atherosclerosis is also considered a chronic inflammatory disease because the endothelial inflammatory damage is ongoing throughout atherosclerosis progression ( in vitro studies of cultured endothelial progenitor cells (EPCs) by Chou et al