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In vivo evaluation of CD38 and CD138 as targets for nanoparticle-based drug delivery in multiple myeloma

Signals are then transferred to inner compartment via receptors located on the plasma membrane initiating a signal transduction pathway to readjust cell metabolism to the new conditions

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Recombinant human insulin-like growth factor-I enhances whole body protein anabolism and significantly diminishes the protein catabolic effects of prednisone in humans without a diabetogenic effect