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By reducing SAM consumption through NNMT inhibition, 5-Amino-1MQ helps preserve methylation capacity for other critical cellular processes, including DNA and histone methylation (epigenetic regulation), neurotransmitter synthesis, and phospholipid metabolism

In particular, Shrivastava and coworkers synthesized a series of PABA derivatives and evaluated them in vitro

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[DOI] [PubMed] [Google Scholar] 12.Sinha K., Pandey S., Das C.R