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After overeating, Wnt/-catenin signal transduction in adipose tissue is inhibited, manifesting as increased expression of inhibitors of the canonical Wnt signalling pathway, such as SFRP2, FRZB/SFRP3, and DKK3, and increased phosphorylation and total GSK-3 levels

Shen L, Jhund PS, Docherty KF, Petrie MC, Anand IS, Carson PE, et al

The data illustrated that the aqueous extract of these species has anti-proliferative activities against MCF-7 cells and MDA-MB-231 cells

k , Oxygen consumption rate, determined by Seahorse bioanalyzer of 4T1 cells overexpressing empty vector, PLGRKT, PLGRKT K147R or PLGRKT 139-147 following pre-treatment for 48 h with DMSO or oligomycin (n = 3 per group)