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[12] Later event-related-potential work with intranasal ACTH(4-10) and desacetyl-alpha-MSH similarly found only limited, task-specific effects on working-memory measures, and in some conditions impaired recall

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In addition to its effects on insulin, GIP plays a crucial role in fat accumulation by promoting the activity of adipocyte-expressed lipoprotein lipase and promoting bone formation by preventing osteoclast apoptosis, as evidenced by the thinner bone trabeculae seen in mice lacking GIP receptors [20,21,22]