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doi: 10.2527/jas.2011-4358 34 MavalliMDDiGirolamoDJFanYRiddleRCCampbellKSvan GroenTet al

Yes, it may interact with certain antibiotics, anticonvulsants, and other medicines

The timeframe for B12 levels to increase following supplementation varies considerably depending on the severity of deficiency, route of administration, dosage, and individual absorption capacity