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5 Therapeutic perspectives: ferroptosis inhibition in periodontitis The intricate pathogenic network linking ferroptosis to periodontitis reveals multiple potential nodes for therapeutic intervention, as summarized in Figure 3

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The integrated analysis of five clinical trials in stage 3 T1D in evaluating the efficacy and safety of teplizumab over the last 20 years showed significantly greater C peptide levels at 1 and 2 years post-treatment in patients treated with teplizumab than in control patients, which implies preservation of cell function