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6.3.2 Therapeutic EVs in ovarian dysfunction: preclinical evidence 6.3.2.1 In vitro studies Evidence derived from in vitro ovarian models provides an important mechanistic framework supporting the feasibility of EVbased strategies for preclinical applications targeting ovarian aging and dysfunction

They can be used in the ROS-responsive gene delivery, upregulation of ROS in malignant cells, scavenging of ROS in inflamed cells, and ROS linked imaging and probes in detections