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GA also stimulates the expressions of TJ proteins, ameliorates cell apoptosis, and oxidative stress, and suppresses the activation of the NF-B/MAPK pathway to alleviate LPS-induced intestinal inflammation in Caco-2 cells [345]

Consequently, this delays wound healing (Zhao et al., 2020), inhibits the phagocytic function of macrophages, and impedes macrophage polarization from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype

10.3389/fimmu.2024.1394108 Summary Keywords rheumatoid arthritis, inflammation resolution, macrophages, fibroblast-like synoviocytes, cytokines Citation Ye X, Ren D, Chen Q, Shen J, Wang B, Wu S and Zhang H (2025) Resolution of inflammation during rheumatoid arthritis

In corneal epithelial cells, this allows quick response to migration signals during wound healing