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Description

Secondary to NTx, we also saw a significant decrease in Hydroxyproline at 5 datapoints

Statistical analysis Data are expressed as mean standard deviation, unless indicated otherwise

Effect of the serum samples on the endothelial cells The endothelial monolayers in 48-well culture plates were exposed for 24 h to the standard culture medium supplemented with the serum sample (20%v/v)

As IKK- is the direct upstream kinase that phosphorylates IB-, leading to its degradation, we next examined whether decreased TNF-induced IB- phosphorylation by H 2 O 2 treatment was due to its effects on IKK- activity