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Interventions using histone deacetylase inhibitors or strategies that suppress histone lactylation mitigate neuropathy in preclinical models, indicating that histone-modifying pathways may serve as potential biomarkers and therapeutic targets (Zhang J

590 Furthermore, -syn oligomers induce lipid peroxidation, while inhibition of lipid peroxidation and reduction of iron-dependent free radical accumulation can reduce the neuronal toxicity induced by -syn oligomers, suggesting the role of ferroptosis in PD

doi: 10.1007/978-1-4419-6033-7_5 190 ZhangMZhangYYChenYWangJWangQLuH

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