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PBS substituted for the primary antibody served as the negative control

Acknowledgements We thank Zhuo-wei Hu (Chinese Academy of Medical Sciences, Peking Union Medical College) for Flag-tagged p62 plasmids and Xiao-bo Qiu (Beijing Normal University) for GFP-RFP-LC3 plasmids

Notably, plant extracts are natural, and multi-compounds products formed through an extraction and separation process from plant and exert positive effects on the integrity of the intestinal barrier with high efficiency and no residue