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La fraction de la dose dpassant cette capacit est limine par voie rnale, la plupart en l'espace de 8 heures aprs application parentrale

This destabilization is primarily mediated by the YTHDF2 reader protein, which translocates modified mRNA to P-bodies or stress granules [42] and recruits the CNOT/CCR4 complex for deadenylation and subsequent degradation [43, 44]