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INTRINSIC AND ADAPTIVE RESISTANCE: THE TUMOR'S MULTI-LAYERED DEFENSE NETWORK Even in scenarios where ATO uptake and some degree of metabolic activation occur, tumor cells often deploy a formidable array of defensive countermeasures that confer intrinsic or adaptive resistance

doi: 10.3389/fpsyt.2022.1070456 Received 14 October 2022 Accepted 20 December 2022 Published 10 January 2023 Volume 13 - 2022 Edited by Murat Ilhan Atagn, anakkale Onsekiz Mart University, Trkiye Reviewed by Kebing Yang, Peking University, China

In contrast, the Oxidized market focuses on traditional, often less sustainable practices that provide immediate gratification and lower initial costs

Also, It inhibits Th17 differentiation (reducing IL-17) while promoting regulatory T-cell (Treg) activity via TGF-1 upregulation