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Also in HCV-related HCC, blood glucose, insulin level and HOMA-IR were higher than in patients with chronic hepatitis and advanced fibrosis

Metformin tablets rarely cause hypoglycemia (low blood sugar) by themselves

10.1016/j.kint.2015.12.029 12 ChangJ.WangY.ShaoL.LabergeR

Additionally, boosting the expression of GPX4, an enzyme that reduces lipid hydroperoxides, could further protect melanocytes from ferroptosis and oxidative damage, leading to improved repigmentation and stabilization of the condition (135138)