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CS Johnston, CG Meyer, JC Srilakshmi

44,45 Numerous target proteins, including histone and non-histone, have been shown to be modified by SIRTs, and participates in the regulation of multiple fundamental cellular functions including glucose, and lipid metabolism, mitochondrial biogenesis, DNA repair, oxidative stress, apoptosis, and inflammation

It is reported that these enzymes are induced, as a protective mechanism (detoxification), under conditions of oxidative stress

Improve Sleep Quality and Immune System Function: When the body produces excess cortisol, it can impair immune function and make it harder to get a good night's rest