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Calderon-Cabrera L, Duran-Galetta MG, Garcia I, Galetta D, Lacruz L, Naranjo R, Perez B, Ferreira E (2008) Determination of the N-acetylcysteine and methionine effects in the cerebellum of rats intoxicated with lead

Studies from the Sikiric laboratory have demonstrated that BPC-157 can counteract the effects of both NO-synthase inhibitors (such as L-NAME) and NO-releasing agents (such as L-arginine) in animal models

This blockade leads to rapid accumulation of norepinephrine within the synaptic cleft and prolonged activation of postsynaptic adrenergic receptors, producing enhanced sympathomimetic activity