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Consequently, targeting glutathione biosynthesis has emerged as a promising therapeutic approach in malignancies such as breast cancer and diffuse large B-cell lymphoma, where disrupting this redox-sensitive signaling network can suppress tumor growth and metastatic potential [50]

PMID: 38811338 Sci BullNeurological impairment is crucial for tire rubber-derived contaminant 6PPDQ-induced acute toxicity to rainbow trout

The resulting single-stranded cDNAs were used as templates in PCR reactions using gene-specific primers to amplify TGR (forward 5-CTATTTCCGTAGACGTCTGT-3 and reverse 5-AATACAGTTTCCTTCCCGTT-3) or GAPDH (forward 5-GTTTTGGTCGTATCGGGAGA-3 and reverse 5-ATGCGTTAGAAACCACGGAC-3)

Mass spectra were obtained by electron ionization at 70 eV using a spectral range of m/z 30-440 and a solvent delay of 6 min