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doi: 10.3390/metabo12050391

Regarding efficacy enhancement, we focus on TCMs role in reversing T-cell exhaustion, reprogramming tumor-associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs), inducing immunogenic cell death (ICD), modulating tumor metabolic reprogramming, and optimizing gut microbiota composition to potentiate systemic antitumor immunity