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Gelber SJ, Hardy MP, Mendis-Handagama SM, Casella SJ: Effects of insulin-like growth factor-I on androgen production by highly purified pubertal and adult rat Leydig cells

As such the overall impact of the manuscript would benefit greatly by detailed editing and potential re-organization. Response: As per your suggestion, we have replaced the section on requirements and detection of dimers with a reference to the original IUPHAR publication