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NaF exposure can also activate the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) pathway and increase nitric oxide (NO) production, leading to the expression of inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-1 beta (IL-1) in testicular and ovarian tissues, resulting in sperm abnormality and ovarian dysfunction [35,36,37]

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Astaxanthin: Sources, extraction, stability, biological activities and its commercial applications - A review