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Enhanced polyamine flux activation leads to elevated energy expenditure via polyamine acetylation, utilizing Acetyl-coenzyme A (acetyl-CoA) to generate acetylpolyamines (Jackson et al., 2003)

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CD157 encodes a molecule that differs significantly in structure and tissue distribution, retaining only some of the enzymatic functions attributed to CD38 ( The primary substrate of CD38 is NAD + , a key molecule in energy production and signaling