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Aside from the traditional protein-based biomarkers, there is an increased interest on the development of analysis methods for newer metabolite-based biomarkers, including TMAO [3]

A meta-analysis focused on complex reproductive histories confirms that for women over 35 with DOR, PCOS, or those undergoing ART cycles, meta-analyses can show meaningful marker improvements, but evidence certainty remains low and effects vary by subgroup and duration

doi: 10.1007/s00125-021-05435-1 18 XuJLloydDJHaleCStanislausSChenMSivitsGet al