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doi: 10.1016/j.cub.2018.02.039 30 AndersonEWilkinsonRFLeeGMellerS

The role of insulin-like growth factor binding proteins in metabolic syndrome Recall that IGFBPs have a very important role, not only in modulating free IGF-1, half-life and localisation, but also by possessing IGF-independent activities mediated by their own receptors

Pancreatic fibroblast growth factor 21 protects against type 2 diabetes in mice by promoting insulin expression and secretion in a PI3K/Akt signaling-dependent manner