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Similarly, mice with p53 mutations that impair the transcriptional activation of p21 , Puma and Noxa , but retain the ability to induce the transcription of certain other p53 target genes, also do not develop tumours spontaneously [38]

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The actor stars in his most provocative role yet, portraying the German Nazi party leader and Adolf Hitler's second-in-command, Hermann Gring

This damage can lead to the thickening of blood vessel walls, known as vascular remodeling, which compromises the vessels ability to transport blood effectively