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The absence of amplified GSTT1 (480 bp) or GSTM1 (271 bp) product (in the presence of the interferon PCR product (170 bp) indicated the respective null genotype for each

Informed consent was obtained from all participants in the study and the study was approved by the Scientific Ethical Committee of Rennes Hospital in France (Avis n 22.185)

In addition, reactive metabolites-proteins adducts are thought to be a principal factor in natural drug-induced liver injury

Concurrently, the combined application of ferroptosis inducers with other therapeutic modalities poses a critical challenge in optimizing combination regimens to maximize therapeutic outcomes