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261 However, normal lysosomal function and the sequestration of cytosolic components during autophagy depend heavily on adequate ATP levels

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Gastroenterology 145 , 10761087 (2013)

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In this context, the present work evaluated the applicability of the commercially available upper MucilAir-HF and lower EpiAlveolar human lung models to be used as in vitro systems within a NAM toolbox to identify the bioactivity (i.e., in vitro PoD derivation) and risk of materials that may reach the respiratory tract and induce lung toxicity

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