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Kayagaki N, et al

More substantial benefits including consistent deep sleep enhancement, robust stress resilience throughout the day, comprehensive sleep architecture optimization, and sustained anxiety reduction typically develop over 1-4 weeks as circadian rhythms stabilize, stress hormone patterns normalize, and neurological adaptations strengthen

Furthermore, mutations in IDH1 at arginine 132 (R132) and in IDH2 at arginine 172 (R172) have also been identified in patients with acute myeloid leukemia (85)