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This effect is probably caused by reduction in the effects of corticosteroids, which prevent muscle growth, and even probably by a reduction in the activity of myostatin

doi: 10.2337/dci24-0015 57 ChengAYFantusIG

So, can a supplement like berberine compete with a prescription GLP-1 drug

We used inverse probability of treatment weighting (IPTW) as the propensity score method aiming to decrease the confounding bias and to balance the baseline characteristics