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Furthermore, when using the minimum dose required to induce premature ventricular contractions (PVCs) in rats as an indicator, its cardiotoxicity was markedly reduced after processing [137].In recent years, advanced analytical techniques such as direct analysis in realtime mass spectrometry (DART-MS) and desorption electrospray ionization mass spectrometry imaging (DESI-MSI), combined with dynamic metabolomics, have been applied for realtime monitoring of processing and spatial distribution analysis of constituents

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