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The most common side effect is a mild stimulant effect, which is why an AM dodge is recommended

The intestinal absorption of carnitine, as well as its renal reabsorption, is primarily mediated by the plasma membrane organic cation transporter novel 2 (OCTN2 SLC22A5) that, among the carnitine-handling transporters, shows the highest affinity toward carnitine

2011 May;28(2):178-87

In studies, l-carnitine has demonstrated the ability to promote oxygenation of heart muscle and maintain healthy enzyme activity, support cardiovascular energy, enhance exercise recovery, and maintain healthy lipid metabolism.* Uses For l-Carnitine Cardiovascular Support: A randomized double-blind placebo-controlled trial involving 101 volunteers indicated that l-carnitine maintained healthy lipid peroxide and lactate dehydrogenase cardiac enzyme activity