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( The flattened diurnal slope and the Adrenal Paradox (where sex steroids may be elevated despite low adrenal precursors) suggest that peripheral tissues and immune cells have taken autonomous control over steroid metabolism, bypassing the central HPA regulation ( In conclusion, the ASI may be considered not as a test for an imaginary Adrenal Exhaustion, but as a hypothesis-driven assessment of the organisms inflammatory resilience

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Peptides are naturally occurring signaling molecules that help cells communicate and regulate essential biological functions throughout the body

10.1186/1471-2164-11-360 224 WataseK.HashimotoK.KanoM.YamadaK.WatanabeM.InoueY.et al