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Maqbool et al., 2022)

The safety profile compares favorably to alternatives such as NSAIDs and corticosteroids, which carry major risks with long-term use

Potential Side Effects BPC-157 remains one of the best-tolerated healing peptides, though minor side effects may include: Temporary injection site irritation Rare headaches or lightheadedness Appetite changes (uncommon) Rare reports of transient fatigue No major systemic toxicity or hormonal disruptions have been reported in current research literature

BPC-157 is not FDA-approved, and the Department of Defenses Operation Supplement Safety program states that it is an unapproved drug rather than a lawful dietary supplement ingredient