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This is valid for all indications of aripiprazole, including its use as an antidepressant, and genotyping can be a valuable tool for personalizing treatment and improving outcomes for patients ( Despite the growing recognition of the clinical and economic benefits of optimizing medication use through pharmacogenomics, CYP2D6 genotyping still faces challenges in widespread implementation in clinical practice, particularly due to the complexity of identifying structural variants

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Specifically, higher TNF- levels are associated with poorer erectile function, as reflected in lower IIEF-5 scores, while a positive correlation exists between TNF- levels and RI, further supporting the hypothesis that inflammation mediates vascular dysfunction in these patients

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