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Taken together, these results suggest that core clock genes are involved in regulating expression of key components in hemostasis and the fibrinolytic system, leading to an increased risk for the development of prothrombotic phenotypes and thus, an increased risk for cerebrovascular events

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On DIV12 the neurons were fixed (4% paraformaldehyde, 3% sucrose, 60 raM PIPES, 25 mM HEPES, 5 mM EGTA, 1 niM MgCl 2 , pH 7.4) for 20 min at room temperature and mounted

The peptide activates endothelial nitric oxide synthase (eNOS) through both VEGFR2-dependent and VEGFR2-independent pathways