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In addition, gene therapy could be used to target genes involved in copper metabolism, thereby optimizing the effects of copper-based therapies

The condition demands a holistic approach that addresses all affected structures, with the goal of strengthening and realigning the knee joint and restoring functional mobility

Glutaredoxin as a chemotherapeutic target Considering the role of Grx1 in supporting RNR activity and the reports showing upregulation of the Grx1 in specific tumours, different groups explored the possibility of targeting Grx1 as a cancer therapy strategy [224]