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These findings support that metformin may protect the cardiovascular system via up-regulating the reverse transport of cholesterol (131)

This internal defense system is crucial for scavenging free radicals and mitigating oxidative stress throughout the body

Iron deposition not only increases A generation in the brain but also promotes A deposition and oxidative stress (OS)-induced toxicity (Lane et al., 2018

Phospholipase A2 releases AA from cell membranes, which is then metabolized by cytochrome P450 monooxygenases, LOXs, and cyclooxygenases into different products, including hydroperoxides and prostaglandins [38]