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Goldberg and Mather, 2012)

We are highlighting amylin as the hottest new mechanism for obesity, Leerink Partners analysts wrote in a Tuesday note to investors, explaining that amylin mostly works as a satiety signal and affects hedonic aspects of eating. The molecule acts on several regions of the brain to lower the feeling of being rewarded after eating

This mechanism has direct relevance for post-surgical recovery, crush injuries, and any condition where vascular compromise threatens tissue viability