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10.1158/1078-0432.ccr-13-2109 178 WuG.WangQ.WangD.XiongF.LiuW.ChenJ.et al (2023)

The authors postulate that therapeutic strategies aimed at modulating glutathione levels or transporter activity might mitigate disease progression in affected individuals

A deficiency of NAD+ may disrupt the circadian rhythm and result in effects such as daytime sleepiness, restless sleep, hormonal imbalances, and mood alterations, among others