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Mitochondrial disease refers to a group of clinically heterogeneous disorders caused by dysfunction in the mitochondrial respiratory chain, often due to mutations in mitochondrial DNA (mtDNA) or nuclear DNA (nDNA) that encodes mitochondrial proteins

doi: 10.1016/j.tplants.2004.10.002 87 Veljovic-JovanovicS

Additionally, 15-d-PGJ 2 induces apoptosis in follicular keratinocytes, as evidenced by increased expression of the pro-apoptotic Bcl-2-associated X protein (BAX) and caspase 3, as well as decreased expression of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2) [181]

Tools for intracellular zinc detection The accurate mapping of zinc within intracellular compartments is crucial for understanding its regulatory functions in organelle function, signaling and homeostasis