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Most preferred that primary care (40%) or addiction medicine (23%) initiate interventions rather than GI/hepatology providers (36%) due to low rates of comfort in AUD counseling (6% vs 13% vs 10%), familiarity with pharmacotherapy (13% vs 6% vs 10%) and discomfort in prescribing pharmacotherapy (38% vs 69% vs 90%, p=0.05) among faculty, fellows, and APP, respectively

New mutations may occur frequently, leading to a heterozygous state in which two or more mtDNA sequence variants (i.e., wild type and one or more mutants) coexist

Your provider can weigh factors, such as the potential health benefits versus the potential side effects and risks, to determine the best treatment for you

Hepatic Gclc KO has been shown to increase levels of serum ALT and AST, suggesting increased liver injury, whereas Chac1 overexpression leads to decreased levels of ALT and AST, indicating a protective effect