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Equally important, the biomarker may be causal to NASH and reveal new pathways that drive the development of liver disease that may represent new biological targets for NASH therapeutics

Acquired Factors and Environmental TriggersWhile genetics play a role, environmental factors like alcohol can also trigger symptoms

Cysteine dependence of Lactobacillus iners is a potential therapeutic target for vaginal microbiota modulation

Estrogen upregulates the expression of Nrf2 via estrogen receptor (ER), which may explain the observation that premenopausal women exhibit different patterns of exercise-induced antioxidant upregulation compared to men [189, 190]