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This suggests a role for NRN1 in reducing oxidative stress and indicates improved cell survival under stress conditions

10.1073/pnas.0801353105 694 WenZ

Vitamin B12 is an essential water-soluble vitamin that plays a key role in red blood cell production, metabolism, and the functioning of the nervous system

Another relevant limitation is that the severity of symptoms was not incorporated into the analysis, which may influence the observed efficacy of antioxidant therapies, particularly in cases with more severe clinical presentations