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Using Pt GSTF8 from poplar as a model enzyme, we use biochemical, structural and computational methods to demonstrate that arGSTs employ a GSH-dependent Brnsted base mechanism for conversion of the LDOX product flavan-3,3,4-triol ( 4 ) or flavan-3-on-4-ol ( 7 ) into flav-2-en-3,4-diol ( 8-B4 ), an equilibrium form of cyanidin

Dietary fibers such as fructo-oligosaccharides (FOS) and galacto-oligosaccharides (GOS) can enhance the gut's production of secondary BAs and SCFAs, both of which support intestinal integrity and may reduce neuroinflammation (Salminen et al., 2021)

In addition, iron overload conditions usually resulted in an elevated RANKL/OPG ratio

Refractoriness of eryptotic red blood cells to Plasmodium falciparum infection: a putative host defense mechanism limiting parasitaemia