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doi:10.1016/j.tem.2017.02.004 PubMed: 28291578 For Research Use Only

The observed risk for metformin-induced vitamin B 12 deficiency demonstrated an additive effect for rs1801222 genotype, with both AG (OR 1.37 [95% CI 1.21, 1.54], I 2 =18.6%) and AA (OR 2.30 [95% CI 1.99, 2.65], I 2 =0%) genotype groups being at increased risk vs the GG group

Takeaway: AOD-9604 should be thought of as an optimized, research-developed analog of HGH fragment 176191 Takeaway AOD-9604 should be thought of as an optimized, research-developed analog of HGH fragment 176191 not an entirely separate peptide, but not exactly the same either

Unlike drugs, the FDA regulates dietary supplements as food, meaning they arent required to prove effectiveness before being marketed